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Abstract

Microsponge drug delivery system as an innovation in Cosmetic world: A Review

Ajay Saraf 1, Amit Dasani2, H. K.Pathan3*

1. Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar (M.P.), India
2. Rajiv Gandhi institute of Pharmacy, Satana (M.P.), India
3. Radharaman College of Pharmacy, Ratibad, Bhopal (M.P.), India

ABSTRACT

The purpose of writing this review to compile the present information’s, current technologies and recent literatures and other contributing factors used to get controlled release of active drug and minimize the drawbacks of topical drug delivery systems like local cutaneous reactions i.e. unpleasant odour, greasiness and skin irritations and fail to reach the systemic circulation in sufficient amount which could be overcome by using a unique, versatile and novel approach Microsponge drug delivery system. Microsponges are highly porous, micro-sized particles with a unique ability for entrapping actives and offers a unique advantage of programmable release and they are biologically safe, yet are simple to produce, making them attractive in the field of topical drug delivery system. Microsponge technology has been explored for various applications like sunscreens, antiacne, antidandruff, OTC (over-the-counter) skin care preparations and skin-depigmentation. Its recently used in oral drugs as well as biopharmaceuticals (peptides, proteins and DNA-based therapeutics) drug delivery and tissue engineering. This article provides an introduction to the various aspects of the structure, development, applications and future of microsponges.

Keywords: Microsponge, Controlled release, Topical drug delivery, Oral drug delivery


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