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Abstract

AN REVIEW OF MICROENCAPSULATION AS NOVEL DRUG DELIVERY

Avalani Gunjan*1, Natasha Sharma1, Mahesh Gupta1, Mahveer Prasad Khinchi 1, Ritesh Verma 2 Subhendu S. Mishra2

1. Department of Pharmaceutics, Kota College of Pharmacy, Kota, Rajasthan
2. Sapience Bioanalytical Research Laboratory, Indrapuri, Bhopal, M.P

ABSTRACT

Microencapsulation products (micro particles) can be defined as small entities that contain an active agent or core material surrounded by a shell or embedded into a matrix structure. Most Microparticle shells or matrices are organic polymers, but lipids and waxes are also used. It is generally accepted that microencapsulation products (micro particles) are larger than 1 micrometer in diameter and can be up to 1000 micrometers. Sustained drug release drug delivery system significantly improve therapeutic efficacy of a drug. Drug release retarding polymers are the key performer in such system. Much of the development in SR drug delivery system is focusing in the preparation and use of polymers with specificity designed macroscopic and microscopic structural and chemical features. Microcapsules continue to be of much interest in controlled release based partly on relative ease of design and formulation and partly on the advantages of micro particulate delivery systems. The latter include sustained release from each individual microcapsule and offer greater uniformity and reproducibility.

Keywords: Microencapsulation, Microcapsule, Sustained release, Controlled release.


[Full Text Article]