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Abstract

DEVELOPMENT AND CHARACTERIZATION OF TRANSFERSOMES LOADED WITH EFINACONAZOLE: FORMULATION AND CHARACTERIZATION

Vishal Singh*, Jaya Pandey, Sona Thakur, Satkar Prasad

Bhabha University, Bhopal (M.P.)

ABSTRACT

This study aimed to develop and characterize transfersomes loaded with efinaconazole for enhanced transdermal delivery. The transfersomes were prepared by optimizing lipid concentration, drug concentration, and stirrer time. The optimized transfersomes were then incorporated into a gel base, and the resulting formulation was characterized for various parameters including average vesicle size, entrapment efficiency, viscosity, drug release kinetics, and extrudability. The optimized gel formulation exhibited promising characteristics for efficient drug delivery. Overall, this research provides valuable insights into the formulation and characterization of transfersome-based gel for transdermal drug delivery applications.

Keywords: Transfersomes, Efinaconazole, Gel formulation, Transdermal delivery, Characterization


[Full Text Article]