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Abstract

GOLDEN PROGRESS: ADVANCEMENTS IN GOLD NANOPARTICLE STUDY

Shivani Chaudhari, Khushboo Gupta*, Smruti Ranjan Dash, Sandip Prasad Tiwari

Faculty of Pharmacy, Kalinga University, Naya Raipur, Chhattisgarh India (492101)

ABSTRACT

Gold nanoparticles are attractive materials in many applications because of their special optical and physical characteristics, like surface plasmon oscillations for identifying, seeing, and feeling. Biomedical applications have advanced significantly recently, offering improved biocompatibility for disease diagnosis and treatment. Numerous functionalizing agents, including polymers, surfactants, ligands, dendrimers, medications, DNA, RNA, proteins, peptides, and oligonucleotides, can be produced and coupled with Au-NPs. In order to broaden and improve gold nanoparticles in targeting pharmaceuticals for photothermal therapy with reduced cytotoxic effects in various malignancies, gene therapy, and many other diseases, this review addressed the usage of gold nanoparticles and the surface functionalization with a wide range of molecules. All things considered, Au-NPs would be a promising drug delivery and therapeutic vehicle.

Keywords: Gold nanoparticle, Gene Therapy, Drug Delivery, Biomedical, Malignancies.


[Full Text Article]