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Abstract

CATALYST AND ENZYMES IN ORGANIC CHEMISTRY AND ITS USES IN FORMULATION OF DRUGS

Upasana Bhatiya, Udit Narayan Rawat, Utkarsh Tiwari, Varun Kumar Jain,
Prateek Jain, Imran Khan*

Adina Institute of Pharmaceutical Sciences, Sagar (M.P.)

ABSTRACT

Enzymes are biological systems' chemical catalysts. They enable organisms to self-replicate and catalyse key metabolic events in a selective and efficient manner. Enzymes are extremely effective and selective biocatalysts found in living creatures, with the exception of ribozymes, which are a tiny group of RNA molecules exhibiting catalytic activity. They come in a wide range of types of processes that they can catalyse, including oxidation–reduction, group transfers inside and between molecules, hydrolysis, isomerization, ligation, bond cleavage, and bond creation. Enzyme-based catalyses also have a higher degree of fidelity, are performed under mild reaction conditions, and are very efficient in terms of number of steps, providing them an advantage over their chemical counterparts. Treatments based on enzyme catalytic activity can convert a wide range of target compounds, allowing for the restoration of normal physiological metabolism. Because of their affinity and specificity qualities, these medicines have significant advantages over traditional therapeutic techniques.

Keywords: Enzymes, Treatments, Formulation, Application.


[Full Text Article]