Abstract

REVIEW ON ANALGESIC POTENTIAL OF TERPENES DERIVED FROM CITRUS FRUIT

Harsh S. Thakur, Himanshu Sahu, Jatin Agrawal, Kailash Pandey, Ashish Jain, Arpit Shrivastava*

Adina Institute of Pharmaceutical Sciences, Sagar (M.P.)

ABSTRACT

Chronic pain is a significant health problem that has a significant influence on worldwide healthcare systems. Despite the fact that this topic has not received the same level of attention as other noncommunicable diseases, it is important to note that contemporary medicine still lacks an effective treatment for chronic pain. Essential oils have been utilised for the prevention of a variety of diseases, including pain management, in this regard. The composition of these odorous goods, which are made from botanically defined raw materials, is diverse and complex. Terpenes, commonly known as terpenoids or isoprenoids, are the biggest class of natural products, with over 55,000 structurally diverse molecules. Terpene-based medications are generated from C5 isoprene units linked in a head-to-tail form from two biosynthetic routes, and worldwide sales of terpene-based pharmaceuticals were roughly US$12 billion in 2002. Anticancer (paclitaxel) and antimalarial (artemisinin) medications are two of the most well-known terpene-based pharmaceuticals. The purpose of this review is to look at the analgesic potential of bioactive chemicals found in citrus fruits.

Keywords: Analgesic Potential, Terpenes, Citrus Fruit.