Login

Journal Front Page

News & Events

  • Call for article for January 2025 issue
    • Submissions of Review, Research Article, Short Communication and Case study are being accepted for the current and future issues before 15 December, 2024 of this journal by online process or editor@ajper.com, or ajper.editor@gmail.com. Further information can be found at www.ajper.com.
  • October 2024 Issue published
    • Dear Researcher, It Pleased to inform you that, Asian Journal of Pharmaceutical Education and Research, has successfully launch Volume 13, Issue 4 (October 2024 Issue). You can find the article on http://ajper.com/current_issue.php Article also invited for the Next coming Issue from your side. For More details Visit: www.ajper.com
  • Application For Reviewer
    • We are now going to reconstitute our editorial board members of Reviewer. Please send your resume at ajper.editor@gmail.com and be a part of the editorial board member as Reviewer.
  • AJPER Impact facor
    • It is to pleasure that Ajper SJIF imact facor has increse from 5.019 to 7.014. Also global impact factor incresed from 0.654 to 0.765.
  • ICV
    • AJPER Rank with Index Copernicus Value 61.10 due to high reputation at International Level

Abstract

FORMULATION, DEVELOPMENT AND EVALUATION OF FLUCONAZOLE HYDROGEL FOR OPTIMUM ANTIFUNGAL TREATMENT

Shubham Badkur*, Dr. Lavakesh Kumar Omray, Dr. Kapil Malviya

Radharaman Institute of Pharmaceutical Science, Bhopal (Madhya Pradesh)

ABSTRACT

The present investigation was prepared topical application of hydrogel containing fluconazole was an attempt to make use of the immense potential of hydrogel as a carrier to improve the permeability. In this research it was to developed and evaluated the Hydrogel containing fluconazole to obtain the optimized formulation which favorable for application as skin delivery system. Fluconazole is used for the treatment of local and systemic fungal infection. But one of the major problems for efficient drug delivery is low penetration rate of fluconazole due to its high solubility and low permeability. The hydrogel of fluconazole was prepared by cold method and evaluated. Gel was evaluated for their clarity, pH, viscosity, spreadability, studies using standard procedure. In vitro release of GF5 formulation was higher than the marketed gel. Based on r2 the GF5 formulation followed Higuchi model for the mechanism of drug release.

Keywords: Antifungal activity, Hydro gel, Fluconazole


[Full Text Article]