Abstract

FORMULATION OF POLYHERBAL FORMULATION FOR TREATMENT OF TOPICAL INFECTION AND ALOPECIA

Ravi Dhakar, Khushi Chouksey, Dr. Kuldeep Ganju

Sagar Institute of Pharmacy and Technology (SIPTec), Bhopal

ABSTRACT

Herb is a plant or part of a plant valued for its medicinal, aromatic, or savoury qualities. Herbs can be viewed as biosynthetic chemical laboratories, producing a number of chemical compounds. Herbal remedies or medicines consist of portions of plants or unpurified plant extracts containing several constituents, which often work together synergistically. Herbal formulations have more demanded in the market. The Hydroalcoholic extracts of Allium cepa L, Withania somnifera, Spinacia oleracea Linn possess almost all the phytochemicals. It could be seen from table no.7.2 that flavonoids and phenols were present in Allium cepa L, Withania somnifera, Spinacia oleracea Linn Hydroalcoholic extract. The total content of flavonoid (equivalent to quercetin) was 0.756 mg/100 mg, 0.639 mg/100 mg and 0.847mg/100mg in Allium cepa L, Withania somnifer, and Spinacia oleracea Linn respectively. The present investigation in this research work, the antifungal activity of polyherbal gel of Allium cepa L, Withania somnifera and Spinacia oleracea Linn were evaluated against Candida albicans pathogens used under present study. The polyherbal gel obtained from plant used to suitably dilute upto the concentrations of 100, 50 and 25 milligram per ml and applied on to the test organism using well diffusion method.

Keywords: Allium cepa L, Withania somnifera, Spinacia oleracea Linn, polyherbal gel, Topical infection