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Abstract

PHYTOCHEMICAL ANALYSIS AND IN VITRO ANTIOXIDANT STUDIES OF TERMINALIA BELLIRICA HYDROALCOHOLIC EXTRACT

Dr. Basanti Jain*, Bhagleshwari

Department of Chemistry, Govt. Maharani Laxmi Bai Girls P.G. Autonomous College, Bhopal (M.P.)

ABSTRACT

The aim of this research is to screen phytochemicals, estimate the phenolic and flavonoid compound content and determine the antioxidant capacity of the extract of Terminalia bellirica leaves. The wellknown test protocol available in the literature was used to determine the qualitative analysis of different phytochemical constituents and the quantitative analysis of total phenols and flavonoids. In various in vitro models, namely 1,1-diphenyl, 2-picryl hydrazyl (DPPH) assays, the hydro alcoholic extract of Terminalia bellirica leaves was studied for antioxidant activity. In the tested models, the extract exhibited dose-dependent free radical scavenging properties. For the DPPH method, the Terminalia bellirica extract showed an IC50 value of 58.29μg/ml, comparable to that of ascorbic acid (IC50=14.33μg/ml). The present study describes Terminalia bellirica's phytochemical profile and antioxidant activity, which will be used for further medicinal applications.

Keywords: Terminalia bellirica, Phytochemical test, Flavonoids content, Antioxidant activity.


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