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Abstract

Synthesis and Antimicrobial Activity of Some 3,5-diaryl-1-(?-sulfamylphenyl)-2- pyrazolines

Neearj Rathore, Amit Nayak

RKDF Collage of Pharmacy, NH-12, Hoshangabad Road , Bhopal (M.P.)

ABSTRACT

A series of 3,5-diaryl-1-(-sulfamylphenyl)-2-pyrazolines derivatives were synthesized by refluxing from various substituted chalcones and 4-hydrazinobenzene sulfonamide hydrochloride in two steps. Compounds were confirmed by physical and spectral data by modern analytical techniques and were evaluated for anti-inflammatory activity. Few Compounds showed moderate activity as compared to standard drug.

Keywords: Pyrazolines, Chalcones, Antimicrobial, Synthesis, Antibacterial, Antifungal


[Full Text Article]