Login

Journal Front Page

News & Events

  • Call for article for January 2025 issue
    • Submissions of Review, Research Article, Short Communication and Case study are being accepted for the current and future issues before 15 December, 2024 of this journal by online process or editor@ajper.com, or ajper.editor@gmail.com. Further information can be found at www.ajper.com.
  • October 2024 Issue published
    • Dear Researcher, It Pleased to inform you that, Asian Journal of Pharmaceutical Education and Research, has successfully launch Volume 13, Issue 4 (October 2024 Issue). You can find the article on http://ajper.com/current_issue.php Article also invited for the Next coming Issue from your side. For More details Visit: www.ajper.com
  • Application For Reviewer
    • We are now going to reconstitute our editorial board members of Reviewer. Please send your resume at ajper.editor@gmail.com and be a part of the editorial board member as Reviewer.
  • AJPER Impact facor
    • It is to pleasure that Ajper SJIF imact facor has increse from 5.019 to 7.014. Also global impact factor incresed from 0.654 to 0.765.
  • ICV
    • AJPER Rank with Index Copernicus Value 61.10 due to high reputation at International Level

Abstract

FLOATING A NEW APPROACH FOR GASTRORETENTIVE DRUG DELIVERY SYSTEM: A REVIEW

Kusum Sharma, Asit Ranjan Sahu, Ankita Srivastava, Ruchi Shukla, Komal Rahevar, D.B. Meshram

Pioneer Pharmacy Degree College, Vadodara-390019, Gujarat, India.

ABSTRACT

Floating drug delivery systems provide local delivery to specific regions like stomach and proximal small intestine and shows better bioavailability, improves patient compliance by increasing the gastric residence time and controlling the drug release. They propose several advantages over conventional dosage forms. The purpose of writing this review article is to introduce the mechanism of floatation in order to attain the gastric retention. In current decades, there have been numerous attempts to overcome the barriers like short gastric residence times and unpredictable gastric emptying times. This article covers different mechanisms, factors affecting, classification and different evaluations of floating drug delivery system. It also includes the advantages, disadvantages and applications of FDDS in detail. This review also summarizes the in vitro techniques to evaluate the drug release from floating system.

Keywords: Bioavailability, Floating drug delivery system, Gastric residence time


[Full Text Article]