Abstract

Swati Patel*, Grijesh Pandey, S.K. Yadav

Swati Patel*, Grijesh Pandey, S.K. Yadav

Technocrats Institute of Technology- Pharmacy Education and Research, Bhopal (M.P.)

ABSTRACT

The most emerging branch in pharmaceutical sciences known as “Pharmaceutical nanotechnology” presents new tools, opportunities and scope, which are expected to have significant applications in disease diagnostics and therapeutics. Recently nano-pharamceuticals reveal enormous potential in drug delivery as carrier for spatial and temporal delivery of bioactive and diagnostics. Nanotechnology, shortened to nanotech, is the study of the controlling of matter on an atomic and molecular scale. Nanoemulsions (also referred as miniemulsions, submicron emulsions, ultrafine emulsions, finedispersed emulsions and so forth) are a group of dispersed particles used as vehicles for pharmaceutical aims and seem to be promising for the future of cosmetics, diagnosis, drug therapies and biotechnologies. Nanoemulsions are transparent or translucent dispersions, having the droplet size of less than 100 nm (the same droplet length-scale as microemulsions) with ultra low interfacial tension, large o/w interfacial areas and long-term physical stability. Literature review reveals that nanoemulsions containing solubilized drugs have been studied extensively as nanocarriers for the treatment of various diseases. Antibiotics, anticonvulsants and antihypertensives are among the drugs solubilized in nanoemulsions. The present review outlines the advantages and disadvantages of nanoemulsion with its preparation methods and therapeutic applications of nano-emulsion based drug delivery system of drugs published over the past decade.

Keywords: Nanoemulsion, Nano-pharamceuticals, Nanocarriers, drug delivery system.