Abstract

FORMULATION DEVELOPMENT AND EVALUATION OF CREAM USING RICE BRAN WAX FOR TOPICAL APPLICATION

Rajeev Malviya*, Dr. M.D. Khirsagar, Dr. A.V. Chandewar

Sant Gadge Baba Amravati University, Amravati

ABSTRACT

In the treatment skin disease, the vehicle (cream, ointment or lotion) may be as important as the active agent. Semisolid preparations are appropriate for patients with sensitive or dry skin who require a nonirritating, nondrying formulation. Patient with dry skin may complain of a “dry” feel with gels. So the people are performing deal with semisolid preparation (ointment, cream and lotion). Patients who have dry skin may be more comfortable with semisolid preparation like cream ointment and lotion, because they have an oily effect. Semisolid preparation work best in patients for the treatment of topical infections. The aim of the present investigation is to formulate and evaluate the best and safe semisolid preparation (cream) in topical composition by using rice bran wax as a base composition for econazole for the treatment of skin disease.

Keywords: Cream, Rice bran wax, econazole