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Abstract

COMPARATIVE IN-VITRO ANTIMICROBIAL ACTIVITY OF HYDROALCOHOLIC EXTRACT OF EMBELIA RIBES (ERE) AND ZIZIPHUS XYLOPYRUS (ZRE)

Sudha Singh*, Pragya Shrivastava

Department of Bioscience, AISECT University, Raisen, (M.P.), India

ABSTRACT

In the present paper we have focus on the worldwide use of traditional plants for the treatment of infectious diseases caused by microorganisms. In early twentieth century, the discovery of antibiotics provide a tool against the microbial infections but due to multiple drug resistance and adverse effects on host including hypersensitivity, immune suppression and allergic reactions shown by antibiotics creates a need of natural medicines with safe and better therapeutic effect. In present work, Hydroalcoholic extracts of Embelia ribes and Ziziphus xylopyrus shows antibacterial activity against Escherichia coli with zone of inhibition lying in the range of 10 to 17 mm and 11 to 19 mm respectively and against Candida albicans with zone of inhibition lying in the range of 8 to 12 mm and 12 to 20 mm respectively. Zone of inhibition of extracts were compared with that of different standards like Ciprofloxacin for antibacterial activity and fluconazole for antifungal activity. The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.

Keywords: Antimicrobial activity, Hydroalcoholic, Embelia ribes, Ziziphus xylopyrus


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