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Abstract

ANTI-HYPERGLYCEMIC ACTIVITY OF MADHUCA LONGIFOLIA KOENG. BARKS

R. V. Savadi, K. S. Akki and S. K. Singh*

Dept of Pharmacognosy and Phytochemistry, K.L.E.S. College of Pharmacy, Vidyanagar, Hubli Karnataka, India.

ABSTRACT

Madhuca longifolia Koeng. is a widely used traditional medicine in many parts of the world for the treatment of various diseases viz. tonic, aphrodisiac,rheumatism, ulcers, and tonsillitis pharyngitis as well as bronchitis It is claimed in traditional medicine that the barks of the plant are used in the treatment of Diabetes mellitus, which are more common in Madhya Pradesh and Chattisgarh states of India. In the present study, the aqueous extract of barks of Madhuca longifolia Koeng was screened for its Antihyperglycemic activity using alloxan induced hyperglycemia model. The aqueous extract at the dose of 500 mg/kg exhibited significant Anti-hyperglycemic activity in alloxan induced hyperglycemia model (p<0.01) indicating that test sample significantly lowered the blood glucose level in Diabetic albino rats, but no effect on normal healthy albino rats. These results have established a pharmacological evidence for the folklore claim of the drug to be used as an anti hyperglycemic agent.

Keywords: Anti-hyperglycemic, Madhuca longifolia Koeng*, Traditional medicine.


[Full Text Article]