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Abstract

A REVIEW: THERAPEUTIC POTENTIAL OF ACONITUM HETEROPHYLLUM

Ritika Soni*, Jitendra Banweer

PhD Scholar, Sanjiv Agrawal global education University Bhopal (M.P)

ABSTRACT

Aconitum heterophyllum (Patrees) is a nonpoisonous and critically endangered medicinal herb found in the northwestern Himalayas that has been used in traditional medicine for centuries. Its roots are harvested for their medicinal properties, which are attributed to the presence of diverse bioactive secondary metabolites, or aconites. This review article provides a comprehensive evaluation of the pharmacological potential of A. heterophyllum, including its classification, distribution, traditional uses, phytochemistry, pharmacology, and conservation measures. Multiple in vitro experimental investigations of A. heterophyllum have demonstrated its analgesic, anti-inflammatory, antiarrhythmic, antiparasitic, and anticancer properties, as well as its effects on the central nervous system. In addition, this review highlights the biosynthetic pathways of A. heterophyllum's key constituents and suggests genetic interventions to enhance the expression levels of desired metabolites for commercial production. Overall, this review highlights the enormous potential of A. heterophyllum for modern drug development and encourages further research to fully understand its pharmacological properties and commercial potential.

Keywords: Aconitum heterophyllum, traditional medicine, pharmacology, drug development, biosynthetic pathways, global pharmacotherapy, natural products.


[Full Text Article]