Abstract

STUDY OF ANTIULCER POTENTIAL OF HYDROALCOHOLIC LEAVES EXTRACT OF STROBILANTHES KUNTHIANA

Anshuman Dubey*, Sailesh Kumar Ghatuary, Satkar Prasad, Monika Parmar

RKDF School of Pharmaceutical Sciences, Bhopal (M.P.)

ABSTRACT

Over the past 200 years, peptic ulcer disease—which includes both stomach and duodenal ulcers has posed a serious threat to the world's population due to its high morbidity and significant mortality. The incidence and frequency of this disease and its consequences have exhibited notable geographic variations according to epidemiological data. Plants have given the human race a variety of incredible medical agents and natural goods that serve as the basis for all pharmaceuticals. Even if many plants are studied for their potential as medicines, more understudied plants need to be investigated for the same goal. It is commonly recognised that Neelakurinji (S. kunthiana) has both decorative and therapeutic qualities. It is evident from animal models that Strobilanthes kunthiana leaf extract exhibits strong anti-ulcer action. When compared to the reference medicine omeprazole, it possesses stomach antisecretory and muco-protective properties. Even when present in quite high amounts, the extract is not hazardous. The presence of flavonoids is likely what causes the anti-ulcer action. To describe and investigate the biological activity of the chemicals found in the extract, more research is being done.

Keywords: Strobilanthes kunthiana, Hydroalcoholic extract, Antiulcer activity.