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Abstract

Pattern of Drug Utilization and Pharmacovigilance Survey on Drugs used in Uncomplicated Malaria in Dewas District of Madhya Pradesh

Rizwana Khan1, Sourabh Jain*2, Karunakar Shukla2

1Central India Institute of Pharmacy, Indore Bypass Rd, Manglaya Sadak, Indore, MP 453771
2*College of Pharmacy, Dr. A. P. J. Abdul Kalam University, Village, Post, Indore Bypass Rd, Arandia, Jhalariya,
MP 452016

ABSTRACT

Adverse drug reactions (ADRs) contribute to ill-health or life-threatening outcomes of therapy during management of infectious diseases. Pharmacovigilance study deals with the complete drug monitoring. It will give idea about the safe use of the drugs and also suggest the drug monitoring and possible adverse drug reactions of any drug in various patients, in various age groups and at different dose regimen. Malaria is a very common and frequent disease in a developing country like India. Approximately every year nearly 40-45% of human beings suffer from the disease and among then nearly 15-18 % have ADRs, The present investigation was carried out in the Department of Malaria, Government District Hospital, Dewas, Madhya Pradesh, India, The study was made to the patient who got treatment from the hospital and drug treatment and results were evaluated. From the data obtained it was concluded that age 11-20 were mostly affected by the malaria and first drug choice is chloroquinine followed by artesunate. As far as ADR is concerned, nausea is most occurring ADR followed by vomiting. As per the assessment about 53.88% of ADRs have been recovered.

Keywords: Adverse drug reactions, Pharmacovigilance, Malaria, Chloroquinine, Artesunate


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