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Abstract

EXTRACTION PHYTOCHEMICAL SCREENING AND QUANTITATIVE STUDY OF BIOACTIVE CONSTITUENTS PRESENT IN AQUEOUS EXTRACT OF CASSIA FISTULA L.

Manoj Kumar Ahirwar, Ritu Thakur Bais*

Department of Botany & Microbiology, Govt. MLB Girls P.G. (Auto.) College, Bhopal, M.P.,
India

ABSTRACT

The potential of higher plants as source for new drugs is still largely unexplored. Among the estimated 250,000-500,000 plant species, only a small percentage has been investigated phytochemically and the fraction submitted to biological or pharmacological screening is even smaller. Cassia fistula also known as the Golden Shower belongs to Fabiaceae family is one such higher plant whole of which is used to treat diarrhea, seeds, flowers and fruits are used to treat skin diseases, fever, abdominal pain and leprosy by traditional people. The present study was intended to explore the phytochemical constituents in aqueous extract of Cassia fistula L to assess its medicinal and therapeutic potential. The fine defatted powder leaves of C. fistula L were subjected to extraction with distilled water by soxhlation followed by concentration then tested for various phytochemical test, TLC analysis and estimation of total polyphenolic compound. The aqueous extract of leaves of C. fistula L were observed to be rich in glycosides, flavonoids, steroids, phenolics amino acids, proteins, saponins and diterpines. The TLC analysis indicated the presence of gallic acid equivalent polyphenols in aqueous extract in addition to presence of 6-7 unknown phytoconstituents. The aqueous leaf extract was reported contain the total polyphenolic compounds in in the range 8.09 mg per 100 mg equivalent to standard gallic acid. Since the aqueous extract are rich in gallic acid equivalent polyphenols indicates the prospects of this plant extract in medicinal and therapeutic significances due to the possible potential, anti-oxidant, anticancer, antimicrobial, antihelmithic, hepatoprotective, immunomodulation, and many other activities. The phetochemicals of this valuable plant could be prospected in development of valuable therapeutics upon further extensive investigation.

Keywords: Cassia fistula L, TLC, TPC, gallic acid.


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