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Abstract

COLON DRUG DELIVERY SYSTEM AND THEIR BENEFITS AND THE CARRIERS FOR DELIVERY OF DRUGS TO COLON: A REVIEW

Supratik Ray1*, Shivakant Shukla1, Dr. A.K. Singhai1, Dr. Subhendu Sekhar Mishra2

1Lakshmi Narain College of Pharmacy, Bhopal (M.P.)

2Kalinga Biomedical Research Institute & Training Establishment, Sambalpur, Odisha

3Gayatri College of Pharmacy, Sambalpur, Odisha, India.

ABSTRACT

The colon drug delivery system is undergoing a designed novel drug delivery system. In this system the drug directly absorbed in colon sites. Normally protein or those drugs which are less absorbed in the stomach or small intestine that type of drugs are targeted to colon site. In the colon site, the bioavailability of drugs is higher than the stomach. Through colon drug delivery system inflammatory bowel disease (IBD), Chron’s disease, as well as asthma and in serious conditions such as colonic cancer. Into the colon through model novel drug formulation drugs are directly targeted to the colon. This review shows the study of benefit criteria for colon targeting of drugs and also the study of formulation type and factor for colon-specific drug delivery systems (CSDDS).

Keywords: Colon drug delivery system, Inflammatory bowel disease, pH of the colon.


[Full Text Article]