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Abstract

IN VITRO ANTI- INFLAMMATORY ACTIVITY OF SEEDS OF TRIGONELLA FOENUM GRAECUM

P. K. Borude*, S. A. Botre, H. S. Deshmukh, V. V. Trivedi

Dattakala College of Pharmacy, Swami-Chincholi, Tal-Daund (Pune)

ABSTRACT

Trigonella foenum-graecum Linn., are used as a spice, in colic, flatulence, dysentery, diarrhea, diabetes, and lipid disorders in India. Ethanol extract, mucilage, and flavonoids of fenugreek seeds were found to have anti-inflammatory, anti-arthritic, and anti-oxidant activities. Ethanolic (90%) extract of the seeds of Trigonella foenum graecum. (Fam:Fabaceae) were studied for their in vitro anti-inflammatory action by Inhibition of albumin denaturation technique in various concentration. The Ethanolic extract of plant shows anti-inflammatory activity as that of standard drug Diclofenac. This activity must be 50% as compared to standard drug Diclofenac.

Keywords: Trigonella foenum graecum, Diclofenac, Invitro Anti-inflammatory activity.


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