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Abstract

ANTI ANEMIC ACTIVITY OF FRUIT OF PRUNUS DOMESTICA IN PHENYLHYDRAZINE INDUCED ANEMIC RAT

Pawan Goud*, Shivendra Raghuwanshi, Ankur Joshi, Sapna Malviya and Anil Kharia

Modern institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

ABSTRACT

The present study was conducted to verify the effect of Prunus domestica on experimentally induced anemia in wistar strain albino rats. 24 no of rats were divided into 4 groups and 6 no of rats each group. Group I received 0.1% CMC solution and served as control, all other groups were given 40 mg/kg of phenyl hydrazine intra peritoneal for 2 days to induce anemia. Group II received 40 mg/kg phenylhydrazine and served as anemic control, Group III received standard drug (vitamin B12) (100mg/kg), Group IV received fruit extract of Prunus domestica (100mg/kg) for 15 days the standard and test drug was given orally. On completion of activity blood was collected through tail vein in EDTA coated tubes for further determination of parameters i.e., RBC count, Heamoglobin count & percentage hematocrit.

Keywords: Anemia, Anti-anemic, Phenylhydrazine, Vit. B12, Prunus domestica.


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