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Abstract

ISOLATION AND IDENTIFICATION OF HELINDICINE ALKALOID FROM THE LEAVES OF HELIOTROPIUM INDICUM

KUMUD SHRIVASTAVA

Department of Chemistry, Govt. M.L.B. Girls College Bhopal (M.P.), INDIA

ABSTRACT

Heliotropium indicum Linn extracted with ethanol and alkaloid fraction was separated on silica gel column using n-hexane, chloroform, ethyl acetate and methanol. extract was concentrated and subjected to TLC, found mixture of three compounds, they were separated by column chromatography. Compound on the bases of spectral analysis identified as a Helindicine alkaloid. Compounds were identified by IR, NMR and mass spectrum. Compound on the bases of spectral analysis identified as a Helindicine alkaloid. Helindicine is a pyrrolizidine alkaloid with unusual structural features.

Keywords: Alkaloid, pyrrolizidine alkaloid, spectral analysis, antineoplastic, antitumor, antibacterial, antifertility, chromatography, indicine.


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