Login

Journal Front Page

News & Events

  • April 2024 Issue delayed
    • Dear Researcher, It Pleased to inform you that, Asian Journal of Pharmaceutical Education and Research, Volume 13, Issue 2 (April 2024) Issue) schedule published on 15 April 2024 is delay due to some technical problem. It will published on 22 April 2024. Sorry for inconvenience. For other details You can vist the website http://www.ajper.com
  • Call for article for April 2024 issue
    • Submissions of Review, Research Article, Short Communication and Case study are being accepted for the current and future issues before 15 March, 2024 of this journal by online process or editor@ajper.com, or ajper.editor@gmail.com. Further information can be found at www.ajper.com.
  • January 2024 Issue published
    • Dear Researcher, It Pleased to inform you that, Asian Journal of Pharmaceutical Education and Research, has successfully launch Volume 13, Issue 1 (January 2024) Issue). You can find the article on http://ajper.com/current_issue.php Article also invited for the Next coming Issue from your side. For More details Visit: www.ajper.com
  • Application For Reviewer
    • We are now going to reconstitute our editorial board members of Reviewer. Please send your resume at ajper.editor@gmail.com and be a part of the editorial board member as Reviewer.
  • AJPER Impact facor
    • It is to pleasure that Ajper SJIF imact facor has increse from 5.019 to 7.014. Also global impact factor incresed from 0.654 to 0.765.
  • ICV
    • AJPER Rank with Index Copernicus Value 61.10 due to high reputation at International Level

Abstract

FORMULATION AND OPTIMIZATION OF SUSTAINED RELEASE FLOATING GASTRO RETENTIVE TABLET OF NIFEDIPINE USING NATURAL POLYMER

Nilesh Jain1, Prabhat Jain*2, Dharmendra Sahu1, Geeta Parkhe2, Surendra K. Jain1

1Sagar Institute of research & technology, Bhopal (M.P.)
2 Scan Research laboratories, Bhopal (M.P.)

ABSTRACT

Aim of the present study was Formulation and optimization of sustained release floating tablet of Nifedipine using natural polymer. Nifedipine is having low oral bioavailability and low half-life of about 2 to 4 hrs hence there is a need to formulate Sustained drug delivery for nifedipine for oral delivery. Nifedipine, a calcium channel blocker antihypertensive drug, is a poorly water soluble drug and belongs to BCS class II. The objective of the research work was to formulate and optimize sustained release matrix tablet using fenugreek a natural polymer, different grade of hydroxy propyl methyl cellulose (HPMC) for optimum delivery of Nifedipine.

Keywords: Nifedipine, Natural Polymer, HPMC, Sustained release


[Full Text Article]