Abstract

PHYTOCHEMICAL SCREENING AND PHARMACOLOGICAL ACTIVITY IN PUNICA GRANATUM

Kanika Dhote^1*, Vinod Dhote², Kapil Khatri¹

¹ Ravishankar College of Pharmacy, Bhopal (M.P)

² Truba Institute of pharmacy, Bhopal (M.P)

ABSTRACT

Pomegranate (Punica granatum) is most important plant belonging to family Lythraceae. A symbol of fecundity and divine femininity emerges, whose fruit rinds, bark and roots are used worldwide astaenicides, owing to alkaloids, and treatment of diarrhea and oral and genital lesions, owing to tannins and astringency. Both the juice and the oil contain numerous and diverse bioflavonoid, which have been shown to be both potently antioxidant and inhibitory of one or both of the enzymes cyclooxygenase (catalyzing arachidonic acid to prostaglandins) and lipoxygenase (catalyzing arachidonic acid to leukotrienes). Extracts of the rinds have been shown to be bactericidal, antiviral, antitumor and use of pomegranates in the treatment of Acquired Immune Deficiency Syndrome (AIDS) owing to their antioxidant properties and botanical uniqueness. This present study is designed to evaluate the phytochemical and pharmacological profile of different extract of Punica granatum.

Keywords: Pomegranate, astaenicides, tannins, cyclooxygenase, lipoxygenase, phytochemical.