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Abstract

Oral thin films: an overview

KanikaDhote1, Vinod Dhote2, Subhendu Mishra1

1 Ravishankar College of Pharmacy, Bhopal(M.P)
2 Truba Institute of pharmacy, Bhopal (M.P)

ABSTRACT

Oral thin films (OTFs) are the most advanced and promising new approaches for drug delivery as it offers more flexibility and comfort. These enable an ease of administration, as there is no need to drink high amounts of liquids or swallow large solid dosage forms Also it improves the efficacy of APIs by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. OTF offers an alternative to tablets, syrups or suppositories for the treatment of vomiting and nausea, especially for the pediatric population. The oral thin-film technology is still in the beginning stages and but most popular because it fulfils all the need of patients. In due course, these formulations having APIs will be commercially launched using the oral film technology. These can be prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering the drug to the systemic circulation via dissolution when contact with liquid is made. Water-soluble polymers are used as film formers for fast dissolving films. It seems that the value on the whole oral thin film market will grow significantly.

Keywords: Oral thin films, vomiting, nausea, hydrophilic polymers


[Full Text Article]