Login

Journal Front Page

News & Events

  • April 2024 Issue delayed
    • Dear Researcher, It Pleased to inform you that, Asian Journal of Pharmaceutical Education and Research, Volume 13, Issue 2 (April 2024) Issue) schedule published on 15 April 2024 is delay due to some technical problem. It will published on 22 April 2024. Sorry for inconvenience. For other details You can vist the website http://www.ajper.com
  • Call for article for April 2024 issue
    • Submissions of Review, Research Article, Short Communication and Case study are being accepted for the current and future issues before 15 March, 2024 of this journal by online process or editor@ajper.com, or ajper.editor@gmail.com. Further information can be found at www.ajper.com.
  • January 2024 Issue published
    • Dear Researcher, It Pleased to inform you that, Asian Journal of Pharmaceutical Education and Research, has successfully launch Volume 13, Issue 1 (January 2024) Issue). You can find the article on http://ajper.com/current_issue.php Article also invited for the Next coming Issue from your side. For More details Visit: www.ajper.com
  • Application For Reviewer
    • We are now going to reconstitute our editorial board members of Reviewer. Please send your resume at ajper.editor@gmail.com and be a part of the editorial board member as Reviewer.
  • AJPER Impact facor
    • It is to pleasure that Ajper SJIF imact facor has increse from 5.019 to 7.014. Also global impact factor incresed from 0.654 to 0.765.
  • ICV
    • AJPER Rank with Index Copernicus Value 61.10 due to high reputation at International Level

Abstract

COMPARATIVE EVALUATION OF IN-VITRO ANTIFUNGAL ACTIVITY OF ETHOSOMAL AND LIPOSOMAL GEL FORMULATED WITH FLUCONAZOLE FOR THE TREATMENT OF DEEP FUNGAL SKIN INFECTIONS

Gajendra Singh Rathore*, Dr. Yuveraj Singh Tanwar, Dr. Pushpendra Singh Naruka

Bhupal Nobles College of Pharmacy, Udaipur (R.J.)

ABSTRACT

Fungal skin infections are caused by different types of fungi, including dermatophytes and yeasts. Fungi invade and grow in dead keratin. Keratin is a protein that makes up your skin, hair and nails. The topical route vied with oral treatment as the most successful innovative research area in drug delivery. The use of lipid vesicles (Ethosomes and liposomes) in delivery systems for skin treatment has attracted increasing attention in recent year. Vesicles allow to control the release rate of drug over an extended time, keeping the drug shielded from immune response and would be able to release just the right amount of drug and keeping the concentration constant for longer period of time. Ethosomes and liposomes are noninvasive delivery carriers that enable drugs to reach the deep skin layer. The purpose of the present study was to assess and compare the in vitro anti-fungal effect of free drug Fluconazole, drug loaded Ethosomes and liposomes on a strain of pathogenic fungus Aspergillus niger.

Keywords: Ethosomes, Liposomes, Fluconazole, Fungal skin infections, In-Vitro Antifungal activity.


[Full Text Article]